"Agave-based liquor" NYT crossword answer is:
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Agave-based liquor is a type of alcoholic beverage made from the agave plant, a succulent native to Mexico and the southwestern United States. It is a popular choice for cocktails, such as margaritas and tequila sunrises, and is also used in a variety of other drinks. Agave-based liquor is known for its smooth, sweet flavor, and is often enjoyed neat or on the rocks.