Former Indigenous inhabitants of modern-day Buffalo NYT crossword answer is:
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The former Indigenous inhabitants of modern-day Buffalo, New York, were the Neutral Nation, an Iroquoian-speaking people who lived in the area for centuries before the arrival of Europeans. The Neutral Nation was a powerful and influential group in the region, and their presence was felt until the mid-17th century when they were driven out by the Iroquois Confederacy. The Neutral Nation left a lasting legacy in the area, and their influence can still be seen in the city's culture and architecture today.